AMSTERDAM, NETHERLANDS – September 22, 2020 – Synaffix B.V., a biotechnology company
enabling antibody-drug conjugates (ADCs) with best-in-class therapeutic index, announces that
it has won the “Best ADC Platform Technology” category at the 2020 World ADC Awards

Synaffix’ ADC platform consists of GlycoConnect™, HydraSpace™ and toxSYN™ which comprise
site-specific technology and payloads to enable best-in-class ADCs.

Synaffix was presented the award during the 2020 World ADC Digital event. The finalists were
shortlisted through a voting pool of over 1,000 individuals, with a panel of distinguished,
independent industry experts from across the ADC field, assessing each finalist to decide the

The judging panel highlighted the following three cornerstone features of the Synaffix ADC
• Consistent delivery of highly competitive ADC product candidates
• Strong commercial and scientific validation (over $420m in out-licensing deals,
at least six ADCs in development with two in clinical trials)
• Compatible and easy to use with any antibody
For the full list of winners, see

Peter van de Sande, CEO of Synaffix said:
“We are greatly honored to be recognized with the award for Best ADC Platform Technology as
voted by our industry peers.”
“Our team has worked passionately to provide cutting-edge ADC-enabling technologies, and
we have now built what we believe to be an industry-leading platform to enable best-in-class
ADC product candidates.”
“Being recognized with this award serves to validate the significant efforts we have already
made towards becoming the most prevalent technology across new clinical-stage ADCs.

For more information, please contact:
Synaffix BV Instinctif Partners
Anthony DeBoer
Director, Business Development

Melanie Toyne-Sewell / Phil Marriage
Tel: +44 207 457 2020

Notes to Editors
About The Synaffix ADC Platform Technology
Synaffix’ proprietary ADC technology platform consists of GlycoConnect™, HydraSpace™ and
toxSYN™ technologies. Both GlycoConnect™ and HydraSpace™ are clinical-stage technologies
that enable best-in-class ADCs with significantly enhanced efficacy and tolerability but without
effector function.
GlycoConnect™ is a conjugation technology that exploits the native antibody glycan for sitespecific
and stable payload attachment and is tunable to DAR1, DAR2 or DAR4 formats.
HydraSpace™ is a compact and highly polar spacer technology designed for hydrophobic
payloads that further enhances therapeutic index.
ToxSYN™ is a linker-payload platform that spans multiple payload classes with MOAs that are
well-understood in the ADC space and facilitates ADC product development.
The combination of these three technologies provides developers with a “one stop” and easyto-
use ADC technology platform, allowing any antibody developer to develop its own
proprietary ADC and any ADC developer to expand its pipeline further and increase its
competitive position.

About Synaffix B.V.
Synaffix B.V. is a biotechnology company that enables ADC product candidates using its clinicalstage,
site-specific ADC technology platform. In addition to GlycoConnect™ and the ADCenhancing
HydraSpace™ technology, the toxSYN™ linker-payload platform rounds out a fully
complementary technology platform that enables any company with an antibody to develop
proprietary best-in-class ADC products under a single license from Synaffix.

The Synaffix platform comes with an IND-ready CMC package to support a rapid timeline to
the clinic. Granted patents covering Synaffix’ technology provide end-to-end protection of the
manufacturing technology as well as the resulting products through at least 2035. The business
model of Synaffix is target-specific technology out-licensing, as exemplified through its existing
deals with ADC Therapeutics, Mersana Therapeutics and Shanghai Miracogen.
Synaffix is backed by a top tier, European, life science-focused investor syndicate that includes
Aravis, BioGeneration Ventures, BOM Capital and M Ventures.
For more information, please visit the website at